º»¹®/³»¿ë
Pituitary Gland
Normal
¡Ý ±¸¼º
∙ant. lobe - adenohypophysis
: secretory epithelial cell·Î ±¸¼º
∙post. lobe - neurohypophysis : unmyelinized n. fiber
¡Ý post. lobe
∙vasopressin (ADH)
∙oxytocin
¡Ý ant. lobe
∙¿¾³¯¿¡´Â acidophils ¼¼ °³ÀÇ cell typeÀ¸·Î ±¸¼º
basophils
chromophobes
∙ÃÖ±Ù immunocytochemistry¿¡ ÀÇÇØ È£¸£¸óÀÇ Á¾·ù¿¡ µû¶ó ±¸º° - 5°¡Áö Áß¿äÇÑ È£¸£¸óÀ» ³»´Â cell type
¨ç growth hormone (somatotrophs)
¨è prolactin (mammotrophs)
¨ç ¨è ¡æ acidophilic
¨é ACTH, MSH, endorphins, lipotropin (corticotrophs)
¨ê TSH (thyrotrophs)
¨ë FSH, LH (gonadotrophs)
¨é ¨ê ¨ë ¡æ basophilic
¨ì ±× ¿ÜÀÇ ÇѰ¡Áö cell type
: nonsecreting cell ¡æ chromophobes¿¡ ¼ÓÇÔ
¢¡ 6°¡Áö cell·Î ±¸¼º
Pathology
1.hyperpituitarism-endocrine system ±â´É Ç×Áø
2.hypopituitarism-endocrine system ±â´É ÀúÇÏ
3.±¹¼ÒÁ¶Á÷¿¡ Áúº´ (local effects)
¼¼ °¡Áö pattern sella turcica
visual field defect
µÎ°³ ³»¾Ð¡è
¡Ý hyperpituitarism - ant. lobe tumor
∙adenoma(¡¦(»ý·«)