colorectal cancer(대장암)에 대한 보고서

2. colorectal cancer
- Colorectal Cancer arises in the Epithelial cells outlining the lumen of the Colon and Rectum.
(a Simple Glandular Columnar Epithelium). Adenocarcinoma.
- Squamous Cell Carcinoma, Sarcoma, Lympoma and Carcinoid Tumors : very rare, less than 2%
of all Colorectal Cancer.
- the transformation of the normal epithelial cell into a cancer cell is a multistage process
: specific genetic alterations (mutations) on specific chromosomes -> a polyp (adenoma) is
formed -> later turns into a cancer.

3. Anatomy & Histology
- The Colon & Rectum or Large Bowel is a storage and absorptive organ.
- the wall is made up of four layers
: the Mucosa (the Epithelium (simple columnar), Lamina Propria and Muscularis Mucosae) ,
the Submucosa, the Muscularis Propria and the Serosa.
- The lower part of the Rectum lacks the Serosa as it goes down and leaves the Peritoneal
cavity. This happens about 10 cm from the Anal Verge. At 2 cm from the Anal Verge there is
an abrupt tra…