본문/내용
Inflammatory response of the host to the uncontrolled multiplication of microorganisms (Various bacterial species, mycoplasmas, chlamydiae, rickettsiae, viruses, fungi, and parasites) invading the distal airways.
Identification of the etiologic microorganism is of primary importance, since this is the key to appropriate antimicrobial therapy. However, because of the serious nature of the infection, patients generally need to be started on antimicrobial therapy immediately, often before laboratory confirmation of the causative agent.
The specific microbial etiology remains elusive in about a third of patients.
The initial choice of antimicrobial therapy is often empirical, based on the setting in which the infection was acquired, the clinical presentation, patterns of abnormality on chest radiography, stains of sputum or other infected body fluids, and knowledge of current patterns of susceptibility to antimicrobial agents.
After the etiologic agent is identified, specific…