º»¹®/³»¿ë
8) IFN-¥ã (gamma interferon)
IFN-¥ã´Â type II interferonÀ̶ó°íµµ ºÎ¸£¸ç, CD4 T cellÀ̳ª CD8 T cells¿¡ ÀÇÇØ ¸¸µé¾îÁ® ¸é¿ª¹ÝÀÀÀ» Á¶ÀýÇϱ⠶§¹®¿¡ immune interferonÀ̶ó°íµµ ºÎ¸¥´Ù. IFN-¥ã´Â T cell, B cell, neutrophils, NK cells, vascular endothelial cell¿¡ ÀÛ¿ëÇÏ¿© ±×µéÀ» Ȱ¼ºÈ½Ãų ¼ö ÀÖÀ¸¸ç, macrophage activating factor·Î ÀÛ¿ëÇÏ¿© Class I and II MHC expressionÀ» Áõ°¡½Ã۱⵵ ÇÑ´Ù. IFN-¥ãµµ ´Ù¸¥ interferonó·³ ¹ÙÀÌ·¯½ºÀÇ Áõ½ÄÀ» ¾ïÁ¦ÇÒ ¼ö ÀÖ´Ù
9) migration inhibition factor (MIF)
MIF´Â ¿°Áõ¹ÝÀÀ Áß¿¡ leukocytes³ª macrophage¿¡ ÀÛ¿ëÇÏ¿© ±×µéÀº ¿°Áõ¹ÝÀÀºÎÀ§¿¡ ¸Ó¹°°Ô ÇÏ´Â ÀÛ¿ëÀ» °¡Áö°í ÀÖ´Ù
10) TGF-¥â (transforming growth factor-¥â)
TGF-¥â´Â tumor cellÀÇ ¼ºÀåÀ» ÃËÁøÇÏ´Â ÀÎÀڷμ ¹ß°ßµÈ »çÀÌÅäÄ«ÀÎÀ¸·Î¼, normal cellÀÌ tumor celló·³ ÀÚ¶ó°Ô ÇÏ´Â ¼ºÁúÀÌ ÀÖ¾î¼ transforming growth factor¶ó°í ºÒ·¶´Ù. ÀÌ ´Ü¹éÁúÀº activated T cell°ú mononuclear phagocytes¿¡ ÀÇÇØ »ý»êµÇ¸ç ºÐÀÚ·®ÀÌ ¾à 28 kDa Á¤µµÀÌ´Ù. TGF-¥â´Â ±× ±â´ÉÀÌ ´Ù¾çÇÏ¿© (pleotropic) ¸¹Àº cell type¿¡ ÀÛ¡¦(»ý·«)