º»¹®/³»¿ë
¢Â Treatment
1) Principle
¨ç Elimination of causative agents or provocative factors
¨è Desensitizing or immunotherapy
¨é Preventive therapy
¨ê Pharmacologic therapy
cf) Aggressive therapy Indications (-severe obstruction)
∙presence of pulsus paradoxus
∙use of accessory muscles
∙marked hyperinflation of the thorax
2) Bronchodilators
¨ç ¥â-Adrenergic drugs
±âÀü : mast cellÀÇ ¥â2 receptor¿¡ ÀÛ¿ë, cAMP»ó½Â, bronchial dilation
Drugs ¢¹ Nonselective : Epinephrine - acute attack½Ã, ¥á,¥â agonist
Isoproterenol - most potent group
Isoetharine - ¥â2 ¿¡ sensitivity°¡Áö³ª ¾àÇÏ´Ù.
¢¹ ¥â2 selective : ºÎÀÛ¿ëÀÌ Àû°í ÀÛ¿ë½Ã°£ÀÌ ±æ´Ù´Â ÀåÁ¡À» °¡Áü.
Resorcinol (metaproterenol, terbutaline)
Saligenin (albuterol, salbuterol ..)
Inhalation : ´ë°³ÀÇ ¾àÁ¦°¡ ÀÌ ÇüÅ·Π³ª¿ÍÀÖÀ¸¸ç parenteral¿¡ ºñÇØ È¿°úÀÇ Â÷À̰¡ ÀûÀ½.
Inhaler »ç¿ë¿¡ °üÇÑ È¯ÀÚÀÇ ±³À°
: ¸ÕÀú ÀܱⷮÀ» ¸ðµÎ ³»¹ñ°Ô Çϰí õõÈ÷ ¾àÀ» µé¿© ¸¶½Ã±â ½ÃÀÛÇÏ¿© °ÅÀÇ total lung¡¦(»ý·«)
Âü°í¹®Çå
1. Cecil¡®s Textbook of Medicine, 19th Edition, Sounders
2. Harrison`s Textbook of Medicine, 13t Edition, McGrowhill