Ovarian cysts and tumors

1.serous cystadenoma

①mucinous처럼 커지지는 않음

②25% malignant change

③gross>external surface - smooth, free

papillary growth를 할경우 특징적
content - thin watery fluid
microscopic> low columnal epi 로 lining, single layer
psammoma body

④origin - ovary의 surface epithelium

2.boderline malignancy

①조직학적으로는 benign이지만 임상적으로는 malignancy

②gross>multilocated cystic lesion with internal papillary excrescences

bilateral
micro>malignant 소견은 나타나나 mitosis 1개/HPF이하
destructive invasion없음
epitherial proliferation with the formation of a`true papillus`
loose cellular cluster
psammoma body많음
stromal necrosis 혹은 inflammation있을경우 well-differentiated ca.생각

③50%이상에서 ovary에 국한

④20%가 30세 이하

3.malignant

①가장 흔한 epitherial malignancy(50%)

②gross> external and internal papillary growth

…(생략)

③differentiation은 중요한 prognostic factor